Krabbe disease (also known as
globoid cell leukodystrophy or
galactosylceramide lipidosis) is a rare, often fatal degenerative disorder that affects the
myelin sheath of the
nervous system. It is a form of
sphingolipidosis, as it involves dysfunctional metabolism of
sphingolipids. This condition is inherited in an
autosomal recessive pattern. The disease is named after the Danish
neurologist (1885–1965).