Sir Thomas Salisbury (or Salusbury) (1564 – September 20, 1586) was one of the conspirators executed for his involvement in the Babington Plot. Salisbury was the elder son of Katheryn of Berain and her first husband, Sir John Salusbury, and was the heir to the Lleweni Estate. He married Margaret Wynn (daughter of Katheryn's third husband, Maurice Wynn), and their daughter, Margaret, eventually inherited Berain, whereas Lleweni went to Thomas's younger brother, Sir John Salusbury. Thomas Salisbury was implicated in the plot to murder Queen Elizabeth I and replace her with Mary, Queen of Scots, and he was executed, along with  Sir Anthony Babington and several others, by being hanged, drawn and quartered.