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Myokine
A
myokine
is one of several hundred
cytokines
or other small
proteins
(~5–20 kDa) and
proteoglycan
peptides
that are produced and released by muscle cells (
myocytes
) in response to
muscular contractions
. They have
autocrine
,
paracrine
and/or
endocrine
effects; their systemic effects occur at
picomolar
concentrations.
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