BepiColombo is a joint mission of the European Space Agency (ESA) and the Japan Aerospace eXploration Agency (JAXA) to the planet Mercury. The mission comprises two satellites to be launched together: the Mercury Planetary Orbiter (MPO) and the Mercury Magnetospheric Orbiter (MMO). The mission will perform a comprehensive study on Mercury, including its magnetic field, magnetosphere, interior structure and surface. It is scheduled to launch in January 2017. The mission was approved in February 2007 as part of the Cosmic Vision programme.

Bepicolombo may refer to:

• asteroid 10387 Bepicolombo
• spacecraft/mission BepiColombo
• Giuseppe (Bepi) Colombo