Cape Serdtse-Kamen (, literally translated as "Cape Heart-Stone") is a headland on the northeastern coast of Chukotka, Russian Federation. It is about 140 km west of Cape Dezhnev, 120 km east of Kolyuchinskaya Bay and about 30 km to the east of the Neskynpil'gyn Lagoon. Nearby is the village of Enurmino.