DART (Direct Analysis in Real Time) is an atmospheric pressure ion source that instantaneously ionizes gases, liquids and solids in open air under ambient conditions. It was developed in 2005 by Laramee and Cody and is now marketed commercially by JEOL and IonSense. It was among the first ambient ionization  techniques not requiring sample preparation, so solid and liquid materials can be analyzed by mass spectrometry in their native state. Ionization can take place directly on the sample surface, such as currency bills, tablets, bodily fluids (blood, saliva and urine), glass, plant leaves, fruits & vegetables and even clothing. Liquids are analyzed by dipping an object (such as a glass rod) into the liquid sample and then presenting it to the DART ion source. Vapors are introduced directly into the DART gas stream.