Frank Signorelli (May 24, 1901 – December 9, 1975) was an US jazz pianist of the 1920s. He was a founder member of the Original Memphis Five in 1917, then joined the Original Dixieland Jazz Band briefly in 1921. In 1927 he played in Adrian Rollini's New York ensemble, and subsequently worked with Eddie Lang, Bix Beiderbecke, Matty Malneck and Paul Whiteman. In 1935 he was part of Dick Stabile's All-America "Swing" Band.