"Hole in the Head" is a song performed by British girl group Sugababes, released on October 13, 2003 as the lead single from their third studio album, Three. It was written by Brian Higgins, Miranda Cooper, Tim Powell, Nick Coler, Niara Scarlett, Keisha Buchanan, Mutya Buena, and Heidi Range, and co-produced by Higgins and Jeremy Wheatley. The song was met with acclaim from critics and was a commercial success, entering the top 10 in ten other countries. It became their second single to chart on the US charts, peaking at number 96 on the Billboard Hot 100 and number 1 on the US dance chart. The first Sugababes single to chart in the US was "Round Round", which reached number 7 on the US dance chart.

Head and lateral line erosion, (HLLE) or hole-in-the-head (HITH) is a disease in fish. Chronic ulcerative dermatopathy or chronic erosive dermatopathy are symptoms of similar conditions with different etiology.