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Kurzweil K250
The Kurzweil K250 a.k.a. "Kurzweil 250", "K250" or "K-250", manufactured by Kurzweil Music Systems was the first electronic musical instrument which produced sound derived from sampled sounds burned onto integrated circuits known as read-only memory (ROM), without the requirement for any type of disk drive.  Acoustic sounds from brass, percussion, string and woodwind instruments as well as sounds created using waveforms from oscillators were utilized. Primarily designed for the professional musician, it was conceived and invented by Raymond Kurzweil, original founder of Kurzweil Computer Products, Inc., Kurzweil Music Systems and Kurzweil Educational Systems with consultation from Stevie WonderLyle Mays, an American jazz pianist; Alan R. Pearlman, founder of ARP Instruments Inc.; and Robert Moog, inventor of the Moog synthesizer.

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