Sint-Genesius-Rode (; , ) is a municipality located in Flanders, one of three regions of Belgium, in the province of Flemish Brabant. The municipality comprises the town of Sint-Genesius-Rode only, and lies between Brussels and Waterloo in Wallonia. On January 1, 2008, the town had a total population of 18,021. The total area is 22.77 km², which gives a population density of 791 inhabitants per km².