The Spatsizi Plateau is a plateau in the upper basin of the Stikine River in north-central British Columbia, Canada. Most of the plateau, which is a sub-plateau of the Stikine Plateau, is enshrined in either Spatsizi Plateau Wilderness Provincial Park or Spatsizi Headwaters Provincial Park. It is flanked on the south and southwest by the Skeena Mountains, on the southeast by the Omineca Mountains, on the northeast by the Stikine Ranges of the Cassiar Mountains, and on the west by the Klastline Plateau (another subplateau of the Stikine Plateau).