Susan Mayer Delfino is a fictional character played by Teri Hatcher on the American Broadcasting Company (ABC) television series Desperate Housewives. The character was created by television producer and screenwriter Marc Cherry. She first appeared in the pilot episode of the series on October 3, 2004, and appeared in every episode until the series finale on May 13, 2012. Susan resides on the fictional Wisteria Lane in Fairview, Eagle State, the primary setting of the show. One of four lead characters, Susan is characterized as being a "notoriously clumsy" romantic with a "magnetic charm." Her storylines tend to focus on her romantic relationships, most notably with Mike Delfino (James Denton), whom she marries twice in the series.