U.S. Route 278 is a parallel route of
U.S. Route 78. It currently runs for 1,074 miles (1,728 km) from
Hilton Head Island, South Carolina to
Wickes, Arkansas at
U.S. Route 71/
U.S. Route 59. It is longer than its parent highway, US 78. US 278 passes through the states of
South Carolina,
Georgia,
Alabama,
Mississippi, and
Arkansas. This highway passes through the cities and towns of
Augusta,
Covington,
Atlanta,
Powder Springs, Georgia;
Hiram, Georgia;
Dallas, Georgia;
Rockmart, Georgia;
Cedartown, Georgia;
Gadsden,
Cullman, Alabama;
Tupelo,
Oxford,
Greenville, Mississippi;
Monticello, and
Hope, Arkansas.