Vayots Dzor (, ), is a province of Armenia. It lies at the southeastern end of the country, bordering the Nakhichevan exclave of Azerbaijan form the west and the Shahumyan Region of the Nagorno-Karabakh Republic from the east. It covers an area of 2,308 km². With a population of only 53,230 (2002 census), it is the most sparsely populated province in the country. The capital and largest city of the province is the town of Yeghegnadzor.