The Wars of Castro were a series of conflicts during the mid-17th century revolving around the ancient city of Castro (located in present-day Lazio, Italy), which eventually resulted in the city's destruction on 2 September 1649. The conflict was a result of a power struggle between the papacy – represented by members of two deeply entrenched Roman families and their popes, the Barberini and Pope Urban VIII and the Pamphili and Pope Innocent X – and the Farnese dukes of Parma, who controlled Castro and its surrounding territories as the Duchy of Castro.