York County, Massachusetts was a county in what is now the U.S. state of Maine. It was established in 1652 when the Massachusetts Bay Colony first asserted territorial claims over the settlements of southern Maine, extending from the Piscataqua River to just east of the mouth of the Presumpscot River in Casco Bay. The county eventually grew to encompass effectively all of present-day Maine, although the interior was claimed by various Abenaki peoples, and the territory east of Penobscot Bay was claimed (and partly occupied) as part of French Acadia. By 1760 most of the Abenaki had either been wiped out or retreated northward toward the Saint Lawrence River, and New France had been conquered in the French and Indian War.