Zayandeh Rud (; formerly, Bābā Sheykh ‘Alī (Persian: بابا شیخ علی), also Romanized as Bābā Sheykh ‘Alī) is a city in the Central District of Lenjan County, Isfahan Province, Iran. At the 2006 census, its population was 9,891, in 2,715 families.

Zāyandé-Rūd or Zāyanderūd (, from زاینده “life giver” and رود “river”), also spelled as Zayandeh-Rood or Zayanderood, is the largest river in the central plateau of Iran. In the early 2010s, the lower reaches of the river dried out completely after several years of seasonal dry-outs.