The Battle of Talikota (, ) (26 January 1565), a watershed battle fought between the Vijayanagara Empire and the Deccan sultanates, resulted in a defeat of Vijayanagara, and ended in greatly weakening one of the greatest Indian Empires originating from the South before the Marathas. Talikota is situated in northern Karnataka, about 80 km to the southeast from the city of Bijapur.