The gens Calpurnia was a plebeian family at Rome, which appears in history during the 3rd century BC. The first of the gens to obtain the consulship was Gaius Calpurnius Piso in 180 BC, but from this time their consulships were very frequent, and the family of the Pisones became one of the most illustrious in the Roman state. Two important pieces of Republican legislation, the lex Calpurnia of 149 BC and lex Acilia Calpurnia of 67 BC were passed by members of the gens.