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Thrombomodulin
Thrombomodulin
(
TM
),
CD
141 or BDCA-3 is an
integral membrane protein
expressed on the surface of endothelial cells and serves as a cofactor for
thrombin
. It reduces
blood coagulation
by converting thrombin to an anticoagulant enzyme from a procoagulant
enzyme
. Thrombomodulin is also expressed on human
mesothelial cell
,
monocyte
and a
dendritic cell
subset.
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