VI or Vi may refer to:

• The submediant chord in music (symbolized "VI" or "vi")
• VI (Circle Jerks album), 1987 album by the Circle Jerks
• VI - Return of the Real, 1996 album by Ice-T
• Beatles VI, 1965 album by The Beatles
• Chicago VI, 1973 album by the American rock band Chicago
• VI (Onslaught album), 2013 album by the English thrash metal band Onslaught
• VI Music, a Puerto Rican record label

vi is a screen-oriented text editor originally created for the Unix operating system. The portable subset of the behavior of vi and programs based on it, and the ex editor language supported within these programs, is described by (and thus standardized by) the Single Unix Specification and POSIX.

.vi is the Internet country code top-level domain (ccTLD) for the U.S. Virgin Islands.