Thutmose (or, more accurately, Djhutmose) was the eldest son of pharaohAmenhotep III and Queen Tiye, who lived during the Eighteenth dynasty of Egypt. His apparent death led to the reign of Akhenaten, his younger brother—as the successor to the Egyptian throne—and the intrigues of the century leading up to Ramesses II, the start and ultimately the failure of Atenism, the Amarna letters, and the changing roles of kingdom's powers.