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Additional
DNA-binding protein
English Wikipedia - The Free Encyclopedia
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DNA-binding protein
DNA-binding proteins
are
proteins
that are composed of
DNA-binding domains
and thus have a specific or general affinity for either single or double stranded
DNA
. Sequence-specific DNA-binding proteins generally interact with the
major groove
of
B-DNA
, because it exposes more
functional groups
that identify a
base pair
. However there are some known
minor groove
DNA-binding ligands such as
netropsin
, distamycin,
Hoechst 33258
,
pentamidine
,
DAPI
and others.
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