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Dihydrotestosterone
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Dihydrotestosterone
Dihydrotestosterone
(commonly abbreviated to
DHT
), or
5a-dihydrotestosterone
(
5a-DHT
), also known as
5a-androstan-17ß-ol-3-one
, is a
sex steroid
and
androgen
hormone
. The enzyme
5a-reductase
synthesizes DHT from
testosterone
in the
prostate
,
testes
,
hair follicles
, and
adrenal glands
. This
enzyme
reduces the 4,5 double-bond of the testosterone. Relative to testosterone, DHT is much more potent as an
agonist
of the
androgen receptor
.
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