****** HELP ******This defect in the function of phagocytes is an autosomal recessive disorder and is characterized by giant granules in myeloid cells and large granular lymphocytes;abnormal microbial killing is due to defective fusion with the phagosome in phagocytes;NK cell activity is similarly impaired.Similar fusion abnormalities in melanocytes causes partial oculocutaneous albinism,in addition to recurrent infection.