Macsyma (Project MAC’s SYmbolic MAnipulator) is one the oldest general purpose
computer algebra systems, which is still widely used. It was originally developed from 1968 to 1982 at
MIT as part of
Project MAC. In 1982, Macsyma was licensed to
Symbolics, and became a commercial product. Simultaneously, it remained available, from
DOE, for academics and US government agencies. DOE version has been maintained by
Bill Schelter, and, under the name of
Maxima, became released under
GPL license from 1999 on.