The National Institute of Science Education and Research (, NISER) is a research institution in Bhubaneswar, Odisha, India. The Prime Minister of India laid the foundation stone on August 28, 2006, establishing the institute along the lines of the IISc in Bangalore, and its five sister institutions, the IISERs that are being established at Pune, Mohali, Kolkata, Bhopal and Thiruvananthapuram in India.