Phospholipase C (PLC) is a class of
enzymes that cleave
phospholipids just before the
phosphate group (see figure). It is most commonly taken to be synonymous with the human forms of this enzyme, which play an important role in
eukaryotic cell physiology, in particular
signal transduction pathways. Thirteen kinds of mammalian phospholipase C are classified into six isotypes (β, γ, δ, ε, ζ, η) according to structure.