The
second season of
Prison Break, an American serial drama television series, commenced airing in the United States on August 21, 2006 on Mondays at 9:00 pm (
EST) on the
Fox Broadcasting Company.
Prison Break is produced by Adelstein-Parouse Productions, in association with Rat Television, Original Television Movie and
20th Century Fox Television. The season contains 22 episodes, and concluded on April 2, 2007. Series creator
Paul Scheuring describes the second season as "
The Fugitive times eight", and likens it to the "second half of
The Great Escape".