Tepelenë is a town and a municipality in Gjirokastër County, southern Albania. It was formed at the 2015 local government reform by the merger of the former municipalities Kurvelesh, Lopës, Qendër Tepelenë and Tepelenë, that became municipal units. The seat of the municipality is the town Tepelenë. The total population is 8,949 (2011 census), in a total area of 431.24 km². The population of the former municipality at the 2011 census was 4,342. The town is located on the left bank of the Vjosë river, about three kilometres downstream from its union with the Drino.