U.S. Route 29 (US 29) is a major north–south route in the Commonwealth of Virginia. It covers from the North Carolina border at the city of Danville to the Key Bridge in Washington, D.C.. US 29 roughly bisects Virginia into eastern and western halves, and along with Interstate 81 in western Virginia, and 85/95 farther east, provides one of the major north–south routes through the Commonwealth.