U.S. Route 64 in North Carolina

U.S. Route 64 (US 64) is the longest numbered route in the U.S. state of North Carolina, running from the Tennessee state line to the Outer Banks. The route passes through the westernmost municipality in the state, Murphy, and one of the most easternmost municipalities, Manteo, making US 64 a symbolic representation of the phrase "from Murphy to Manteo" which is used to refer to the expanse of the state. The highway is a major east-west route through the central and eastern portion of the state.