Acid–base homeostasis is the part of biologic homeostasis (for example, human homeostasis) concerning the proper balance between acids and bases, also called body pH. The body is very sensitive to its pH level, so strong mechanisms exist to maintain it. Outside the acceptable range of pH, proteins are denatured and digested, enzymes lose their ability to function, and death may occur. The principles of general acid–base equilibrium apply in the physiology of living systems.