The
anterior commissure (also known as the
precommissure) is a bundle of nerve fibers (
white matter), connecting the two temporal lobes of the cerebral hemispheres across the midline, and placed in front of the columns of the
fornix. The great majority of fibers connecting the two hemispheres travel through the
corpus callosum, which is over 10 times larger than the anterior commissure, and other routes of communication pass through the
hippocampal commissure or, indirectly, via subcortical connections. Nevertheless, the anterior commissure is a significant pathway that can be clearly distinguished in the brains of all mammals. The anterior commissure plays a key role in pain and pain sensation, more specifically sharp, acute pain. It also contains decussating fibers from the olfactory tracts, vital for the sense of smell and chemoreception. The anterior commissure works with the
posterior commissure to link the two cerebral hemispheres of the brain and also interconnects the amygdalas and temporal lobes, contributing to the role of memory, emotion, speech and hearing. It also is involved in olfaction, instinct, and sexual behavior.