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dihydrodeoxycorticosterone
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Dihydrodeoxycorticosterone
5a-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5a-pregnan-20-one, is an endogenous progestogen and neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5a-reductase type I. DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABAA receptor, and is known to have anticonvulsant effects.
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