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Additional
inositol triphosphate
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Inositol trisphosphate
Inositol trisphosphate
or
inositol 1,4,5-trisphosphate
(also commonly known as
triphosphoinositol
; abbreviated
InsP
3
or
Ins3P
or
IP
3
), together with
diacylglycerol
(DAG), is a
secondary messenger
molecule used in
signal transduction
and
lipid signaling
in
biological cell
s. While DAG stays inside the membrane, IP
3
is soluble and diffuses through the cell. It is made by
hydrolysis
of
phosphatidylinositol 4,5-bisphosphate
(PIP
2
), a
phospholipid
that is located in the
plasma membrane
, by
phospholipase C
(PLC).
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