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Additional
mutated
English Wikipedia - The Free Encyclopedia
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Mutation
In
biology
, a
mutation
is a permanent alteration of the
nucleotide sequence
of the
genome
of an
organism
,
virus
, or
extrachromosomal DNA
or other genetic elements. Mutations result from damage to
DNA
which is not
repaired
, errors in the process of
replication
, or from the
insertion
or
deletion
of segments of DNA by
mobile genetic elements
. Mutations may or may not produce discernible changes in the observable characteristics (
phenotype
) of an organism. Mutations play a part in both normal and abnormal biological processes including:
evolution
,
cancer
, and the development of the
immune system
, including
junctional diversity
.
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