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Additional
paratope
English Wikipedia - The Free Encyclopedia
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Paratope
[File:Immunoglobulin basic unit.svg|thumb| 1.
Fab region
2.
Fc region
3.
Heavy chain
4.
Light chain
with one variable (V
L
) and one constant (C
L
) domain
5.
Fv region
with paratope
6. Hinge regions]] A
paratope
, also called an
antigen-binding site
, is a part of an
antibody
which recognizes and binds to an
antigen
. It is a small region (of 15 to 22
amino acids
) of the antibody's
Fv region
, part of the
fragment antigen-binding
(Fab region), and contains parts of the antibody's
heavy
and
light chains
. Each arm of the Y shape of an antibody monomer is tipped with a paratope, which is a set of
complementarity determining regions
.
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