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Additional
small GTPase
English Wikipedia - The Free Encyclopedia
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Small GTPase
Small GTPases
are a family of
hydrolase
enzymes
that can
bind
and
hydrolyze
guanosine triphosphate
(GTP). They are a type of
G-proteins
found in the
cytosol
that are
homologous
to the alpha subunit of
heterotrimeric G-proteins
, but unlike the alpha subunit of G proteins, a small GTPase can function independently as a hydrolase enzyme to bind to and hydrolyze a guanosine triphosphate (GTP) to form
guanosine diphosphate
(GDP). The most well-known members are the
Ras GTPases
and hence they are sometimes called
Ras superfamily GTPases
.
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