A
syncytium or
symplasm (; plural
syncytia; from
Greek:
σύν (syn) = "together" +
κύτος (kytos) = "box, i.e. cell") is a
multinucleated cell that can result from multiple cell fusions of uninuclear cells (i.e., cells with a single nucleus), in contrast to a
coenocyte, which can result from multiple nuclear divisions without accompanying
cytokinesis. The term may also refer to cells interconnected by specialized membrane with
gap junctions, as seen in the
heart muscle cells and certain smooth muscle cells, which are synchronized electrically in an action potential.