Monoclonal antibody therapy is a form of
immunotherapy that uses
monoclonal antibodies (mAb) to bind
monospecifically to certain
cells or
proteins. This may then stimulate the patient's
immune system to attack those cells. Alternatively, in
radioimmunotherapy a radioactive dose localizes on a target cell line, delivering lethal chemical doses. More recently antibodies have been used to bind to molecules involved in
T-cell regulation to remove inhibitory pathways that block T-cell responses, known as immune checkpoint therapy.