Translate:
English
Chinese (S)
Chinese (T)
Croatian
Dutch
French
German
Hebrew
Italian
Japanese
Korean
Portuguese
Russian
Serbian
Spanish
Swedish
Turkish
Additional
vitamin D receptor
English Wikipedia - The Free Encyclopedia
Download this dictionary
Calcitriol receptor
The
calcitriol receptor
, also known as the
vitamin D
receptor (
VDR
) and also known as
NR1I1
(nuclear receptor subfamily 1, group I, member 1), is a member of the
nuclear receptor
family of
transcription factors
. Upon activation by vitamin D, the VDR forms a
heterodimer
with the
retinoid-X receptor
and binds to
hormone response elements
on
DNA
resulting in
expression
or
transrepression
of specific
geneproducts
. The VDR not only regulates transcriptional responses but also involved in
microRNA
-directed post transcriptional mechanisms. In humans, the vitamin D receptor is encoded by the
VDR
gene
.
See more at Wikipedia.org...
© This article uses material from
Wikipedia
®
and is licensed under the
GNU Free Documentation License
and under the
Creative Commons Attribution-ShareAlike License