E. I. du Pont de Nemours and Company, commonly referred to as DuPont, is an American chemical company that was founded in July 1802 as a gunpowder mill by Éleuthère Irénée du Pont.

Dupont, DuPont, Du Pont, duPont, or du Pont is a common French surname. It may refer to:

• Alfred I. duPont Hospital for Children, Wilmington, Delaware
• E. I. du Pont de Nemours and Company, commonly known as DuPont, one of the world's largest chemical companies
• Du Pont Motors
• Gilbert Dupont, a French stock brokerage part of retail banking network Crédit du Nord
• ST Dupont, a French manufacturer of fine writing instruments, men's jewellery and more notably lighters
• Dupont Brewery, a brewery located in Tourpes (Leuze-en-Hainaut), Belgium