Abitibi-Témiscamingue is an administrative region located in southwestern Québec, Canada, along the border with Ontario. It became part of the province in 1898. It has a land area of 57,674.26 km² (22,268.16 sq mi). The region is divided into five regional county municipalities (French: municipalité régionale de comté, or MRC) and 79 municipalities. Its economy continues to be dominated by resource extraction industries. These include logging, mining all along the rich geologic Cadillac Fault between Val d'Or and Rouyn-Noranda, as well as agriculture.

For the region of Quebec, see Abitibi-Témiscamingue.

Abitibi—Témiscamingue is a federal electoral district in Quebec, Canada, that has been represented in the House of Commons of Canada since 2004. The area was also represented by the electoral district of Témiscamingue from 1968 until 2004.