Amapa can refer to:

• Amapá is one of the states of Brazil.
• Amapá (city), a municipality in that Brazilian state.
• Amapa, Nayarit, a town in the Mexican state of Nayarit.
• Amapa, Amapa morada: common name for the tree Handroanthus impetiginosus, which ranges from northern Mexico to Argentina.
• Amapa: a large tree (Parahancornia fasciculata) from the Amazon Rainforest. It belongs to the Dogbane family (Apocynaceae). It is used to treat wounds, asthma and bronchitis.

Amapá is a state located in the northern region of Brazil. It is the second least populous state and the eighteenth largest by area. Located in the far northern part of the country, Amapá is bordered clockwise by French Guiana to the north, the Atlantic Ocean to the east, Pará to the south and west, and Suriname to the northwest. The capital and largest city is Macapá.