Cape Catastrophe is a headland located at the south east tip of Jussieu Peninsula on Eyre Peninsula in South Australia. It is one of the natural features named by Matthew Flinders in memory of the eight crew who were lost from a cutter that capsized sometime after being launched from the HM Sloop Investigator to search for water on 21 February 1802. Flinders also nominated the headland as being the western point of the mouth of Spencer Gulf. It is currently located within the protected area known as the Memory Cove Wilderness Protection Area.