Americans with disabilities are one of the largest minority groups in the United States. Although the US does not have universal healthcare, Americans with disabilities can generally find adequate levels of subsidized support from a variety of sources, generally at the regional level. While most rural areas — especially in the Great Plains region — have little or no government-organized medical support infrastructure for the permanently disabled indigent population, most major urban centers have healthcare systems. The rights of Americans with disabilities are protected by the Americans with Disabilities Act of 1990.