U.S. Route 12 (US 12) is a part of the United States Numbered Highway System that runs from Aberdeen, Washington, to Detroit, Michigan. In the U.S. state of Indiana, it is part of the state road system. US 12 enters the state concurrent with US 20 and US 41 in Whiting. The of US 12 that lie within Indiana serve as a major conduit. Some of the highway is listed on the National Highway System. Various sections are rural two-lane highway, urbanized four-lane undivided highway and one-way streets. The easternmost community along the highway is Michiana Shores at the Michigan state line.