This article is about the first Fall River Railroad. For the second Fall River Railroad, (1874 to 1896), see Fall River Railroad (1874).

The Fall River Railroad was incorporated in 1846 as a merger between the Fall River Branch Railroad, the Middleborough Railroad Corporation and the Randolph & Bridgewater Railroad Corporation. The railroad ran from Fall River through Middleborough and Bridgewater to South Braintree where it connected to the Old Colony Railroad line.