Guadalupe is a town in Maricopa County, Arizona, United States. Since its founding, it has been known as a center of Yaqui culture and it is home to many religious festivals. The town motto, "where three cultures flourish," recognizes the towns roots in the Yaquis, Mexicans and descendants of the original farmers. Nestled between Phoenix and Tempe, the 2010 census listed the population of the town as 5,523. Guadalupe was founded around 1900 by Yaqui Indians, who fled their homeland in Sonora to avoid oppression by the Mexican government of Porfirio Diaz. Respectful visitors are welcome to observe these ceremonies, although photography is forbidden. Guadalupe is primarily a residential area; most residents commute to other parts of the Phoenix area to work.